Venice, Italy, 25th July 2018 / Sciad NewswireDOULIX ™, the synthetic biology toolbox to design, analyse and synthesise biological systems, today announced the launch of its new DNA assembly tool, the MoCLO wizard. The computer-aided wizard facilitates the design and assembly of synthetic DNA constructs by the user. It is a result of collaboration between Doulix and Dr Emmanuele Severi, University of York, funded by EU project TOPCAPI.

Doulix is a comprehensive virtual toolkit for synthetic biology that allows users an easy way to design and validate custom DNA constructs before synthesising and delivering them either as dsDNA fragments or ready-to-use plasmids. This new tool will enable synthetic biologists to rapidly design and synthesise MoCLO CIDAR Level 0 constructs, choosing from hundreds of validated standard biological parts or using custom DNA sequences. By automating this step, the time spent by synthetic biologists on DNA design will be reduced and efficiency of their research increased. The MoCLO wizard is fully integrated with the CIDAR MoCLO collection developed by Prof. Densmore, University of Boston, USA, and the iGEM collection curated by the iGEM Registry, Cambridge, USA. 

Davide De Lucrezia, Doulix managing director, commented: “The MoCLO wizard is the latest addition to our toolbox for synthetic biology. Coupled with a broad collection of standard biological parts, we expect to significantly cut the prototyping time by allowing the user to move directly from design to synthesis.”

Dr Emmanuele Severi, University of York, adds: “Doulix seamlessly brings together design and gene synthesis, straight from board-to-bench. Together with the user-friendliness of the tool, this makes Doulix a competitive resource for synthetic biologists.”

The new tool has applications across synthetic biology research but will be particularly relevant to early-career synthetic biologists including those teams competing in this year’s iGEM. To find out more on how this tool could accelerate your research click here.


For further information, contact:

Davide De Lucrezia, Managing Director
T: +39 06 62 28 3945

Sciad Communications, Media Relations:
Juliette Craggs
T: +44 (0)20 7470 8801

Notes to Editors

Double Helix Technologies (DOULIX ™) is a trademark and a business unit of EXPLORA BIOTECH Srl dedicated to the development of innovative enabling technologies to unlock the full potential of forward biological engineering. Information about Doulix is available at

TOPCAPI is a collaboration between academic and industrial partners from around Europe coordinated by the University of Manchester that will harness the biosynthetic power of actinomycete bacteria to create microbial cell factories for the production of high-value pharmaceuticals, in particular antibiotics. This project received funding from the European Union’s Horizon 2020 Research and Innovation Programme under Grant Agreement No. 720793.

Got an innovation you need bringing to life?

We’d love to hear from you! Head to our contact page to start a conversation.

Photo of Juliette Craggs